2 recent papers with really interesting results!
Click here to read the full paper on computationally designed VLPs.
- RBD can be efficiently displayed on the mi3 VLP via SpyTag/SpyCatcher
- RBD-SpyVLP is reactive to monoclonal antibodies isolated from recovered patients
- RBD-SpyVLP induces a strong ACE2-blocking and neutralising antibody response in mouse models
- RBD-SpyVLP is highly immunogenic and induces strong neutralising antibody response in pigs
Click here to read the full paper on Bacteriophage VLPs.